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Abuse is a side view shooter game released in 1995 for the MS-DOS platform. Developed and published by Crack dot Com, it is set within a science fiction and futuristic genre framework. The game presents a narrative scenario where the player assumes the role of Nick Vrenna, a prisoner held in a clandestine facility.

Players control Nick as he navigates the prison's interconnected environments, which are presented from a side perspective. The primary objective is to escape the complex after a containment breach releases a mutagenic agent, transforming most other inhabitants into hostile creatures. Progression is structured through a series of levels, requiring the player to fight through these enemies while solving environmental puzzles to access new areas. Key gameplay systems involve run and gun style combat using a variety of futuristic weapons and careful platforming to traverse the industrial and laboratory settings. The player must manage ammunition and health resources while engaging enemies that often attack in groups.

The game's pacing involves moving through tightly designed corridors and chambers, with the complexity arising from navigating the maze-like layout under constant threat. The side view perspective allows for precise aiming and movement, which is central to both combat and exploration. The player's journey involves uncovering the secrets of the facility while systematically battling the infected monsters that now populate it.